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Caterina Finizia

Professor, adjungerad

Caterina Finizia
Professor, adjungerad
caterina.finizia@orlss.gu.se

Postal Address: Sahlgrenska universitetssjukhuset, 41345 Göteborg
Visiting Address: Gröna stråket 9 5 vån su/sahlgrenska , 41345 Göteborg


Department of Otorhinolaryngology at Institute of Clinical Sciences (More Information)
Sahlgrenska Universitetssjukhuset
413 45 Göteborg
0313429121
Visiting Address: Gröna stråket 9 5 vån SU/Sahlgrenska , 413 45 Göteborg

About Caterina Finizia

Professor Caterina Finizia
Dept of ENT/H&N Surgery; Sahlgrenska University Hospital

Since 1994 working as an ENT-specialist at Sahlgenska Univeristy Hospital (SU)

Present postgraduate appointment ENT-specialist Sahlgrenska University Hospital 20%, chief of internship education SU 60%, 20% of working hours assigned to research work as ENT professor. Principle supervisor of eight accomplished PhD theses.

Head and neck cancer treatment
Clinical and translational research applied to risk organs and intervention for complications following head and neck cancer treatment

Purpose and Aims
The overall goal of our proposed project is to reduce incidence and severity of complications following treatment for head and neck cancer (HNC) by identifying patients at risk and implementing interventions based on clinical and translational research.

In Sweden, approximately 1300 patients are diagnosed with HNC annually. They are generally treated with chemoradiotherapy (CRT) and/or surgery. The oncologic treatment yields severe complications in up to 50% of the patients, affecting communication, swallowing and mouth-opening ability (trismus). There is currently a significant gap in our knowledge on how to best care for these patients, both in terms of how to manage the complications and how to prevent them.


Improve health related quality of life
During the last decade, we have focused on identifying and treating long-term complications following oncologic treatment in HNC patients, aiming to improve health related quality of life (HRQL), optimising rehabilitation and reduce health care costs. Based on this research, we have now expanded our research aims with focus on identification of patients and organs at risk using genetic and dose studies and prevention studies of HNC treatment complications. We have also developed and/or translated several validated patient reported instruments, which have then been used to assess outcomes and efficacy in clinical intervention studies.

Our team includes otolaryngologists, oncologists, radiologists, odontologists, speech-language pathologists, medical physicists and mathematicians. We are therefore in an excellent position to fill the knowledge gap identified above. Our strategy for doing so is defined in the following.

Specific aims:
1. To clarify the mechanisms involved in trismus and dysphagia complications by using whole genome genetic analysis as well as targeted gene analysis in head and neck cancer patients
2. To identify risk structures for radiation induced trismus and dysphagia through predictive modelling of normal tissue response and to avoid these conditions through altered treatment planning of radiotherapy
3. To develop and implement more efficient interventions and measures of complications after oncologic treatment for head and neck cancer

 

Latest publications

Community listeners' perceptions of voice function post-radiotherapy for laryngeal cancer.
Liza Bergström, Elizabeth C Ward, Caterina Finizia
International Journal of Speech-Language Pathology, Journal article 2018
Journal article

Image-based Data Mining to Probe Dosimetric Correlates of Radiation-induced Trismus
W. Beasley, M. Thor, A. McWilliam, A. Green, R. Mackay et al.
International Journal of Radiation Oncology Biology Physics, Journal article 2018
Journal article

Showing 1 - 10 of 82

2019

2018

Community listeners' perceptions of voice function post-radiotherapy for laryngeal cancer.
Liza Bergström, Elizabeth C Ward, Caterina Finizia
International Journal of Speech-Language Pathology, Journal article 2018
Journal article

Image-based Data Mining to Probe Dosimetric Correlates of Radiation-induced Trismus
W. Beasley, M. Thor, A. McWilliam, A. Green, R. Mackay et al.
International Journal of Radiation Oncology Biology Physics, Journal article 2018
Journal article

Showing 1 - 10 of 82

Page Manager: Katarina Olinder Eriksson|Last update: 11/9/2012
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